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The use of energy curing technology in graphic arts is still marginal, even if it has all the characteristics to become a very important technique mainly for high printing speed, increasing quality, reduced VOC release. In order to develop these characteristics and to satisfy unmet needs, a continuous improvement of the components of the formulations is required. Photoinitiators are key components for the success of a formulation. Some required characteristics of photoinitiators are high reactivity, good stability in the formulations, no release of odorous photodecomposition derivatives, low migration from the cured formulations. In graphic arts two main different applications have been developed: the overprint varnishes (OPV), that are mainly constituted by clear coatings and the inks made up of pigmented systems. Both UV curable inks and OPVs play a large role in the development of various types of food packaging materials. One of the critical issues regarding food packaging applications is the potential migration of the ink and coating components, including both the photoinitiators and the co-initiators into the foodstuff.